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Glutamine Supplementation Attenuates Ethanol-Induced Disruption of Apical Junctional Complexes in Colonic Epithelium and Ameliorates Gut Barrier Dysfunction and Fatty Liver in Mice

Previous in vitro studies showed that glutamine (Gln) prevents acetaldehyde-induced disruption of tight junctions and adherens junctions in Caco-2 cell monolayers and human colonic mucosa. In the present study, we evaluated the effect of Gln supplementation on ethanol-induced gut barrier dysfunction...

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Publicado en:J Nutr Biochem
Main Authors: Chaudhry, Kamaljit K., Shukla, Pradeep K., Mir, Hina, Manda, Bhargavi, Gangwar, Ruchika, Yadav, Nikki, McMullen, Megan, Nagy, Laura E., Rao, RadhaKrishna
Formato: Artigo
Idioma:Inglês
Publicado: 2015
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4691434/
https://ncbi.nlm.nih.gov/pubmed/26365579
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jnutbio.2015.08.012
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