Rapid identification and evaluation of neoantigen-reactive T cell receptors from single cells.

Engineered T cells expressing tumor-specific T cell receptors (TCRs) are emerging as a mode of personalized cancer immunotherapy that requires identification of TCRs against the products of known driver mutations and novel mutations in a timely fashion. We present a non-viral and non-next generation...

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Detalles Bibliográficos
Publicado en:J Immunother
Autores principales: Paria, Biman C., Levin, Noam, Lowery, Frank, Pasetto, Anna, Deniger, Drew C., Parkhurst, Maria R., Yossef, Rami, Kim, Sanghyun P., Florentin, Maria, Ngo, Lien, Ray, Satyajit, Krishna, Sri, Robbins, Paul F., Rosenberg, Steven A.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2021
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7725897/
https://ncbi.nlm.nih.gov/pubmed/33086340
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/CJI.0000000000000342
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