Antigen Experienced T Cells from Peripheral Blood Recognize p53 Neoantigens

PURPOSE: The purpose of this study was to evaluate antigen experienced T cells in peripheral blood lymphocytes (PBL) for responses to p53 neoantigens. EXPERIMENTAL DESIGN: PBLs from patients with a mutated TP53 tumor were sorted for antigen-experienced T cells and in vitro stimulation (IVS) was perf...

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Publicado en:Clin Cancer Res
Autores principales: Malekzadeh, Parisa, Yossef, Rami, Cafri, Gal, Paria, Biman C., Lowery, Frank J., Jafferji, Mohammad, Good, Meghan L., Sachs, Abraham, Copeland, Amy R., Kim, Sanghyun P., Kivitz, Scott, Parkhurst, Maria R., Robbins, Paul F., Ray, Satyajit, Xi, Liqiang, Raffeld, Mark, Yu, Zhiya, Restifo, Nicholas P., Somerville, Robert P.T., Rosenberg, Steven A., Deniger, Drew C.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2020
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7424598/
https://ncbi.nlm.nih.gov/pubmed/31996390
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-19-1874
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