Unique neoantigens arise from somatic mutations in patients with gastrointestinal cancers

Immunotherapies can mediate regression of human tumors with high mutation rates, but responses are rarely observed in patients with common epithelial cancers. This raises the question of whether patients with these common cancers harbor T lymphocytes that recognize mutant proteins expressed by autol...

Description complète

Enregistré dans:
Détails bibliographiques
Publié dans:Cancer Discov
Auteurs principaux: Parkhurst, Maria R., Robbins, Paul F., Tran, Eric, Prickett, Todd D., Gartner, Jared J., Jia, Li, Ivey, Gabriel, Li, Yong F., El-Gamil, Mona, Lalani, Almin, Crystal, Jessica S., Sachs, Abraham, Groh, Eric, Ray, Satyajit, Ngo, Lien T., Kivitz, Scott, Pasetto, Anna, Yossef, Rami, Lowery, Frank J., Goff, Stephanie L., Lo, Winifred, Cafri, Gal, Deniger, Drew C., Malekzadeh, Parisa, Ahmadzadeh, Mojgan, Wunderlich, John R., Somerville, Robert P.T., Rosenberg, Steven A.
Format: Artigo
Langue:Inglês
Publié: 2019
Sujets:
Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7138461/
https://ncbi.nlm.nih.gov/pubmed/31164343
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2159-8290.CD-18-1494
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires