Unique neoantigens arise from somatic mutations in patients with gastrointestinal cancers

Immunotherapies can mediate regression of human tumors with high mutation rates, but responses are rarely observed in patients with common epithelial cancers. This raises the question of whether patients with these common cancers harbor T lymphocytes that recognize mutant proteins expressed by autol...

Descrición completa

Gardado en:
Detalles Bibliográficos
Publicado en:Cancer Discov
Main Authors: Parkhurst, Maria R., Robbins, Paul F., Tran, Eric, Prickett, Todd D., Gartner, Jared J., Jia, Li, Ivey, Gabriel, Li, Yong F., El-Gamil, Mona, Lalani, Almin, Crystal, Jessica S., Sachs, Abraham, Groh, Eric, Ray, Satyajit, Ngo, Lien T., Kivitz, Scott, Pasetto, Anna, Yossef, Rami, Lowery, Frank J., Goff, Stephanie L., Lo, Winifred, Cafri, Gal, Deniger, Drew C., Malekzadeh, Parisa, Ahmadzadeh, Mojgan, Wunderlich, John R., Somerville, Robert P.T., Rosenberg, Steven A.
Formato: Artigo
Idioma:Inglês
Publicado: 2019
Assuntos:
Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7138461/
https://ncbi.nlm.nih.gov/pubmed/31164343
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2159-8290.CD-18-1494
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares