Rapid identification and evaluation of neoantigen-reactive T cell receptors from single cells.

Engineered T cells expressing tumor-specific T cell receptors (TCRs) are emerging as a mode of personalized cancer immunotherapy that requires identification of TCRs against the products of known driver mutations and novel mutations in a timely fashion. We present a non-viral and non-next generation...

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Bibliografiska uppgifter
I publikationen:J Immunother
Huvudupphovsmän: Paria, Biman C., Levin, Noam, Lowery, Frank, Pasetto, Anna, Deniger, Drew C., Parkhurst, Maria R., Yossef, Rami, Kim, Sanghyun P., Florentin, Maria, Ngo, Lien, Ray, Satyajit, Krishna, Sri, Robbins, Paul F., Rosenberg, Steven A.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2021
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7725897/
https://ncbi.nlm.nih.gov/pubmed/33086340
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/CJI.0000000000000342
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