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Rapid identification and evaluation of neoantigen-reactive T cell receptors from single cells.

Engineered T cells expressing tumor-specific T cell receptors (TCRs) are emerging as a mode of personalized cancer immunotherapy that requires identification of TCRs against the products of known driver mutations and novel mutations in a timely fashion. We present a non-viral and non-next generation...

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Detalhes bibliográficos
Publicado no:J Immunother
Main Authors: Paria, Biman C., Levin, Noam, Lowery, Frank, Pasetto, Anna, Deniger, Drew C., Parkhurst, Maria R., Yossef, Rami, Kim, Sanghyun P., Florentin, Maria, Ngo, Lien, Ray, Satyajit, Krishna, Sri, Robbins, Paul F., Rosenberg, Steven A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7725897/
https://ncbi.nlm.nih.gov/pubmed/33086340
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/CJI.0000000000000342
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