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Rapid identification and evaluation of neoantigen-reactive T cell receptors from single cells.

Engineered T cells expressing tumor-specific T cell receptors (TCRs) are emerging as a mode of personalized cancer immunotherapy that requires identification of TCRs against the products of known driver mutations and novel mutations in a timely fashion. We present a non-viral and non-next generation...

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Publicat a:J Immunother
Autors principals: Paria, Biman C., Levin, Noam, Lowery, Frank, Pasetto, Anna, Deniger, Drew C., Parkhurst, Maria R., Yossef, Rami, Kim, Sanghyun P., Florentin, Maria, Ngo, Lien, Ray, Satyajit, Krishna, Sri, Robbins, Paul F., Rosenberg, Steven A.
Format: Artigo
Idioma:Inglês
Publicat: 2021
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7725897/
https://ncbi.nlm.nih.gov/pubmed/33086340
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/CJI.0000000000000342
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