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Rapid identification and evaluation of neoantigen-reactive T cell receptors from single cells.

Engineered T cells expressing tumor-specific T cell receptors (TCRs) are emerging as a mode of personalized cancer immunotherapy that requires identification of TCRs against the products of known driver mutations and novel mutations in a timely fashion. We present a non-viral and non-next generation...

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Bibliografiske detaljer
Udgivet i:J Immunother
Main Authors: Paria, Biman C., Levin, Noam, Lowery, Frank, Pasetto, Anna, Deniger, Drew C., Parkhurst, Maria R., Yossef, Rami, Kim, Sanghyun P., Florentin, Maria, Ngo, Lien, Ray, Satyajit, Krishna, Sri, Robbins, Paul F., Rosenberg, Steven A.
Format: Artigo
Sprog:Inglês
Udgivet: 2021
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7725897/
https://ncbi.nlm.nih.gov/pubmed/33086340
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/CJI.0000000000000342
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