Context-Dependent Requirement of Euchromatic Histone Methyltransferase Activity during Reprogramming to Pluripotency

Methylation of histone 3 at lysine 9 (H3K9) constitutes a roadblock for cellular reprogramming. Interference with methyltransferases or activation of demethylases by the cofactor ascorbic acid (AA) facilitates the derivation of induced pluripotent stem cells (iPSCs), but possible interactions betwee...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Stem Cell Reports
Prif Awduron: Vidal, Simon E., Polyzos, Alexander, Chatterjee, Kaushiki, Ee, Ly-sha, Swanzey, Emily, Morales-Valencia, Jorge, Wang, Hongsu, Parikh, Chaitanya N., Amlani, Bhishma, Tu, Shengjiang, Gong, Yixiao, Snetkova, Valentina, Skok, Jane A., Tsirigos, Aristotelis, Kim, Sangyong, Apostolou, Effie, Stadtfeld, Matthias
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Elsevier 2020
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7724475/
https://ncbi.nlm.nih.gov/pubmed/32976761
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2020.08.011
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