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Cellular trajectories and molecular mechanisms of iPSC reprogramming

The discovery of induced pluripotent stem cells (iPSCs) has solidified the concept of transcription factors as major players in controlling cell identity and provided a tractable tool to study how somatic cell identity can be dismantled and pluripotency established. A number of landmark studies have...

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Detalles Bibliográficos
Publicado en:Curr Opin Genet Dev
Main Authors: Apostolou, Effie, Stadtfeld, Matthias
Formato: Artigo
Idioma:Inglês
Publicado: 2018
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6252123/
https://ncbi.nlm.nih.gov/pubmed/29925040
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.gde.2018.06.002
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