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Prospective Isolation of Rare Poised iPSC Intermediates Reveals Principles of Cellular Reprogramming

Cellular reprogramming converts differentiated cells into induced pluripotent stem cells (iPSCs). However, this process is typically very inefficient, complicating mechanistic studies. We identified and molecularly characterized rare, early intermediates poised to reprogram with up to 95% efficiency...

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Dades bibliogràfiques
Publicat a:Cell Stem Cell
Autors principals: Schwarz, Benjamin A., Cetinbas, Murat, Clement, Kendell, Walsh, Ryan M., Cheloufi, Sihem, Gu, Hongcang, Langkabel, Jan, Kamiya, Akihide, Schorle, Hubert, Meissner, Alexander, Sadreyev, Ruslan I., Hochedlinger, Konrad
Format: Artigo
Idioma:Inglês
Publicat: 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6086589/
https://ncbi.nlm.nih.gov/pubmed/30017590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2018.06.013
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