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Prospective Isolation of Rare Poised iPSC Intermediates Reveals Principles of Cellular Reprogramming
Cellular reprogramming converts differentiated cells into induced pluripotent stem cells (iPSCs). However, this process is typically very inefficient, complicating mechanistic studies. We identified and molecularly characterized rare, early intermediates poised to reprogram with up to 95% efficiency...
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| Publicat a: | Cell Stem Cell |
|---|---|
| Autors principals: | , , , , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2018
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6086589/ https://ncbi.nlm.nih.gov/pubmed/30017590 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2018.06.013 |
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