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Comparison of reprogramming factor targets reveals both species-specific and conserved mechanisms in early iPSC reprogramming
BACKGROUND: Both human and mouse fibroblasts can be reprogrammed to pluripotency with Oct4, Sox2, Klf4, and c-Myc (OSKM) transcription factors. While both systems generate pluripotency, human reprogramming takes considerably longer than mouse. RESULTS: To assess additional similarities and differenc...
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| Publicado en: | BMC Genomics |
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| Autores principales: | , , , , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
BioMed Central
2018
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6303873/ https://ncbi.nlm.nih.gov/pubmed/30577748 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-018-5326-1 |
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