X Chromosome Dosage Influences DNA Methylation Dynamics during Reprogramming to Mouse iPSCs

A dramatic difference in global DNA methylation between male and female cells characterizes mouse embryonic stem cells (ESCs), unlike somatic cells. We analyzed DNA methylation changes during reprogramming of male and female somatic cells and in resulting induced pluripotent stem cells (iPSCs). At a...

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Publicado en:Stem Cell Reports
Autores principales: Pasque, Vincent, Karnik, Rahul, Chronis, Constantinos, Petrella, Paula, Langerman, Justin, Bonora, Giancarlo, Song, Juan, Vanheer, Lotte, Sadhu Dimashkie, Anupama, Meissner, Alexander, Plath, Kathrin
Formato: Artigo
Lenguaje:Inglês
Publicado: Elsevier 2018
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5995367/
https://ncbi.nlm.nih.gov/pubmed/29681539
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2018.03.019
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