X Chromosome Dosage Influences DNA Methylation Dynamics during Reprogramming to Mouse iPSCs

A dramatic difference in global DNA methylation between male and female cells characterizes mouse embryonic stem cells (ESCs), unlike somatic cells. We analyzed DNA methylation changes during reprogramming of male and female somatic cells and in resulting induced pluripotent stem cells (iPSCs). At a...

Full description

Saved in:
Bibliographic Details
Published in:Stem Cell Reports
Main Authors: Pasque, Vincent, Karnik, Rahul, Chronis, Constantinos, Petrella, Paula, Langerman, Justin, Bonora, Giancarlo, Song, Juan, Vanheer, Lotte, Sadhu Dimashkie, Anupama, Meissner, Alexander, Plath, Kathrin
Format: Artigo
Language:Inglês
Published: Elsevier 2018
Subjects:
Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5995367/
https://ncbi.nlm.nih.gov/pubmed/29681539
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2018.03.019
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items