X Chromosome Dosage Influences DNA Methylation Dynamics during Reprogramming to Mouse iPSCs

A dramatic difference in global DNA methylation between male and female cells characterizes mouse embryonic stem cells (ESCs), unlike somatic cells. We analyzed DNA methylation changes during reprogramming of male and female somatic cells and in resulting induced pluripotent stem cells (iPSCs). At a...

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Detalhes bibliográficos
Publicado no:Stem Cell Reports
Main Authors: Pasque, Vincent, Karnik, Rahul, Chronis, Constantinos, Petrella, Paula, Langerman, Justin, Bonora, Giancarlo, Song, Juan, Vanheer, Lotte, Sadhu Dimashkie, Anupama, Meissner, Alexander, Plath, Kathrin
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5995367/
https://ncbi.nlm.nih.gov/pubmed/29681539
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2018.03.019
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