Chargement en cours...

Stage-specific regulation of reprogramming to iPSCs by Wnt signaling and Tcf proteins

Wnt signaling is intrinsic to mouse embryonic stem cell self-renewal. Therefore it is surprising that reprogramming of somatic cells to induced pluripotent stem cells (iPSCs) is not strongly enhanced by Wnt signaling. Here, we demonstrate that active Wnt signaling inhibits the early stage of reprogr...

Description complète

Enregistré dans:
Détails bibliographiques
Auteurs principaux: Ho, Ritchie, Papp, Bernadett, Hoffman, Jackson A., Merrill, Bradley J., Plath, Kathrin
Format: Artigo
Langue:Inglês
Publié: 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3700671/
https://ncbi.nlm.nih.gov/pubmed/23791530
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2013.05.015
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!