Manipulation of KLF4 Expression Generates iPSCs Paused at Successive Stages of Reprogramming

The detailed mechanism of reprogramming somatic cells into induced pluripotent stem cells (iPSCs) remains largely unknown. Partially reprogrammed iPSCs are informative and useful for understanding the mechanism of reprogramming but remain technically difficult to generate in a predictable and reprod...

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Publicado no:Stem Cell Reports
Main Authors: Nishimura, Ken, Kato, Tetsuo, Chen, Chen, Oinam, Lalhaba, Shiomitsu, Emi, Ayakawa, Daisuke, Ohtaka, Manami, Fukuda, Aya, Nakanishi, Mahito, Hisatake, Koji
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4235142/
https://ncbi.nlm.nih.gov/pubmed/25418733
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2014.08.014
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