Manipulation of KLF4 Expression Generates iPSCs Paused at Successive Stages of Reprogramming

The detailed mechanism of reprogramming somatic cells into induced pluripotent stem cells (iPSCs) remains largely unknown. Partially reprogrammed iPSCs are informative and useful for understanding the mechanism of reprogramming but remain technically difficult to generate in a predictable and reprod...

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Publicat a:Stem Cell Reports
Autors principals: Nishimura, Ken, Kato, Tetsuo, Chen, Chen, Oinam, Lalhaba, Shiomitsu, Emi, Ayakawa, Daisuke, Ohtaka, Manami, Fukuda, Aya, Nakanishi, Mahito, Hisatake, Koji
Format: Artigo
Idioma:Inglês
Publicat: Elsevier 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4235142/
https://ncbi.nlm.nih.gov/pubmed/25418733
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2014.08.014
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