X Chromosome Dosage Influences DNA Methylation Dynamics during Reprogramming to Mouse iPSCs

A dramatic difference in global DNA methylation between male and female cells characterizes mouse embryonic stem cells (ESCs), unlike somatic cells. We analyzed DNA methylation changes during reprogramming of male and female somatic cells and in resulting induced pluripotent stem cells (iPSCs). At a...

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Vydáno v:Stem Cell Reports
Hlavní autoři: Pasque, Vincent, Karnik, Rahul, Chronis, Constantinos, Petrella, Paula, Langerman, Justin, Bonora, Giancarlo, Song, Juan, Vanheer, Lotte, Sadhu Dimashkie, Anupama, Meissner, Alexander, Plath, Kathrin
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier 2018
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5995367/
https://ncbi.nlm.nih.gov/pubmed/29681539
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2018.03.019
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