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Nascent Induced Pluripotent Stem Cells Efficiently Generate Entirely iPSC-Derived Mice while Expressing Differentiation-Associated Genes

The ability of induced pluripotent stem cells (iPSCs) to differentiate into all adult cell types makes them attractive for research and regenerative medicine; however, it remains unknown when and how this capacity is established. We characterized the acquisition of developmental pluripotency in a su...

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Detalhes bibliográficos
Publicado no:Cell Rep
Main Authors: Amlani, Bhishma, Liu, Yiyuan, Chen, Taotao, Ee, Ly-Sha, Lopez, Peter, Heguy, Adriana, Apostolou, Effie, Kim, Sang Yong, Stadtfeld, Matthias
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6664440/
https://ncbi.nlm.nih.gov/pubmed/29420174
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2017.12.098
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