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Small molecules facilitate rapid and synchronous iPSC generation
The reprogramming of somatic cells into induced pluripotent stem cells (iPSCs) upon overexpression of OCT4, KLF4, SOX2, and c-MYC (OKSM) provides a powerful system to interrogate basic mechanisms of cell fate change. However, iPSC formation with standard methods is protracted and inefficient, result...
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| Publicado no: | Nat Methods |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4326224/ https://ncbi.nlm.nih.gov/pubmed/25262205 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nmeth.3142 |
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