Probabilistic Modeling of Reprogramming to Induced Pluripotent Stem Cells

Reprogramming of somatic cells to induced pluripotent stem cells (iPSCs) is typically an inefficient and asynchronous process. A variety of technological efforts have been made to accelerate and/or synchronize this process. To define a unified framework to study and compare the dynamics of reprogram...

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Detalhes bibliográficos
Main Authors: Lin L. Liu, Justin Brumbaugh, Ori Bar-Nur, Zachary Smith, Matthias Stadtfeld, Alexander Meissner, Konrad Hochedlinger, Franziska Michor
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2016-12-01
Colecção:Cell Reports
Assuntos:
induced pluripotent stem cells
reprogramming
mathematical/probabilistic modeling
birth-death transition processes
Acesso em linha:http://www.sciencedirect.com/science/article/pii/S2211124716316540
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