A molecular roadmap of cellular reprogramming into iPS cells

Factor-induced reprogramming of somatic cells into induced pluripotent stem cells (iPSCs) is inefficient, complicating mechanistic studies. Here, we studied defined intermediate cell populations poised to becoming iPSCs by genome-wide analyses. We show that induced pluripotency elicits two transcrip...

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Autors principals: Polo, Jose M., Anderssen, Endre, Walsh, Ryan M., Schwarz, Benjamin A., Nefzger, Christian M., Lim, Sue Mei, Borkent, Marti, Apostolou, Effie, Alaei, Sara, Cloutier, Jennifer, Bar-Nur, Ori, Cheloufi, Sihem, Stadtfeld, Matthias, Figueroa, Maria Eugenia, Robinton, Daisy, Natesan, Sridaran, Melnick, Ari, Zhu, Jinfang, Ramaswamy, Sridhar, Hochedlinger, Konrad
Format: Artigo
Idioma:Inglês
Publicat: 2012
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3608203/
https://ncbi.nlm.nih.gov/pubmed/23260147
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2012.11.039
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