Aberrant silencing of imprinted genes on chromosome 12qF1 in mouse induced pluripotent stem cells

Induced pluripotent stem cells (iPSCs) have been generated by enforced expression of defined sets of transcription factors in somatic cells. It remains controversial whether iPSCs are molecularly and functionally equivalent to blastocyst-derived embryonic stem cells (ESCs). By comparing genetically...

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Bibliografiske detaljer
Main Authors: Stadtfeld, Matthias, Apostolou, Effie, Akutsu, Hidenori, Fukuda, Atsushi, Follett, Patricia, Natesan, Sridaran, Kono, Tomohiro, Shioda, Toshi, Hochedlinger, Konrad
Format: Artigo
Sprog:Inglês
Udgivet: 2010
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3987905/
https://ncbi.nlm.nih.gov/pubmed/20418860
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature09017
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