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Aberrant silencing of imprinted genes on chromosome 12qF1 in mouse induced pluripotent stem cells

Induced pluripotent stem cells (iPSCs) have been generated by enforced expression of defined sets of transcription factors in somatic cells. It remains controversial whether iPSCs are molecularly and functionally equivalent to blastocyst-derived embryonic stem cells (ESCs). By comparing genetically...

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Hlavní autoři: Stadtfeld, Matthias, Apostolou, Effie, Akutsu, Hidenori, Fukuda, Atsushi, Follett, Patricia, Natesan, Sridaran, Kono, Tomohiro, Shioda, Toshi, Hochedlinger, Konrad
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3987905/
https://ncbi.nlm.nih.gov/pubmed/20418860
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature09017
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