KLF4 is involved in the organization and regulation of pluripotency-associated 3D enhancer networks

Cell fate transitions are accompanied by global transcriptional, epigenetic and topological changes driven by transcription factors (TFs), as is exemplified by reprogramming somatic cells to pluripotent stem cells (PSCs) via expression of OCT4, KLF4, SOX2 and cMYC. How TFs orchestrate the complex mo...

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Publicado no:Nat Cell Biol
Main Authors: Di Giammartino, Dafne Campigli, Kloetgen, Andreas, Polyzos, Alexander, Liu, Yiyuan, Kim, Daleum, Murphy, Dylan, Abuhashem, Abderhman, Cavaliere, Paola, Aronson, Boaz, Shah, Veevek, Dephoure, Noah, Stadtfeld, Matthias, Tsirigos, Aristotelis, Apostolou, Effie
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7339746/
https://ncbi.nlm.nih.gov/pubmed/31548608
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41556-019-0390-6
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