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KLF4 is involved in the organization and regulation of pluripotency-associated 3D enhancer networks

Cell fate transitions are accompanied by global transcriptional, epigenetic and topological changes driven by transcription factors (TFs), as is exemplified by reprogramming somatic cells to pluripotent stem cells (PSCs) via expression of OCT4, KLF4, SOX2 and cMYC. How TFs orchestrate the complex mo...

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發表在:Nat Cell Biol
Main Authors: Di Giammartino, Dafne Campigli, Kloetgen, Andreas, Polyzos, Alexander, Liu, Yiyuan, Kim, Daleum, Murphy, Dylan, Abuhashem, Abderhman, Cavaliere, Paola, Aronson, Boaz, Shah, Veevek, Dephoure, Noah, Stadtfeld, Matthias, Tsirigos, Aristotelis, Apostolou, Effie
格式: Artigo
語言:Inglês
出版: 2019
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7339746/
https://ncbi.nlm.nih.gov/pubmed/31548608
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41556-019-0390-6
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