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H3K27ac bookmarking promotes rapid post-mitotic activation of the pluripotent stem cell program without impacting 3D chromatin reorganization
During self-renewal, cell type-defining features are drastically perturbed in mitosis and must be faithfully reestablished upon G1 entry; a process that remains largely elusive. Here, we characterized at a genome-wide scale the dynamic transcriptional and architectural resetting of mouse pluripotent...
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| Publicado no: | Mol Cell |
|---|---|
| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8052294/ https://ncbi.nlm.nih.gov/pubmed/33730542 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2021.02.032 |
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