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KLF4 is involved in the organization and regulation of pluripotency-associated 3D enhancer networks

Cell fate transitions are accompanied by global transcriptional, epigenetic and topological changes driven by transcription factors (TFs), as is exemplified by reprogramming somatic cells to pluripotent stem cells (PSCs) via expression of OCT4, KLF4, SOX2 and cMYC. How TFs orchestrate the complex mo...

詳細記述

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書誌詳細
出版年:Nat Cell Biol
主要な著者: Di Giammartino, Dafne Campigli, Kloetgen, Andreas, Polyzos, Alexander, Liu, Yiyuan, Kim, Daleum, Murphy, Dylan, Abuhashem, Abderhman, Cavaliere, Paola, Aronson, Boaz, Shah, Veevek, Dephoure, Noah, Stadtfeld, Matthias, Tsirigos, Aristotelis, Apostolou, Effie
フォーマット: Artigo
言語:Inglês
出版事項: 2019
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7339746/
https://ncbi.nlm.nih.gov/pubmed/31548608
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41556-019-0390-6
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