Characterization of the p300 Taz2–p53 TAD2 Complex and Comparison with the p300 Taz2–p53 TAD1 Complex

The p53 tumor suppressor is a critical mediator of the cellular response to stress. The N-terminal transactivation domain of p53 makes protein interactions that promote its function as a transcription factor. Among those cofactors is the histone acetyltransferase p300, which both stabilizes p53 and...

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Bibliographic Details
Published in:Biochemistry
Main Authors: Miller Jenkins, Lisa M., Feng, Hanqiao, Durell, Stewart R., Tagad, Harichandra D., Mazur, Sharlyn J., Tropea, Joseph E., Bai, Yawen, Appella, Ettore
Format: Artigo
Language:Inglês
Published: 2015
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7722985/
https://ncbi.nlm.nih.gov/pubmed/25753752
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.5b00044
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