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p53 N-terminal phosphorylation: a defining layer of complex regulation

The p53 tumor suppressor is a critical component of the cellular response to stress. As it can inhibit cell growth, p53 is mutated or functionally inactivated in most tumors. A multitude of protein–protein interactions with transcriptional cofactors are central to p53-dependent responses. In its act...

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Detalhes bibliográficos
Main Authors: Jenkins, Lisa M. Miller, Durell, Stewart R., Mazur, Sharlyn J., Appella, Ettore
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3499055/
https://ncbi.nlm.nih.gov/pubmed/22505655
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgs145
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