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p53 N-terminal phosphorylation: a defining layer of complex regulation
The p53 tumor suppressor is a critical component of the cellular response to stress. As it can inhibit cell growth, p53 is mutated or functionally inactivated in most tumors. A multitude of protein–protein interactions with transcriptional cofactors are central to p53-dependent responses. In its act...
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| Main Authors: | , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Oxford University Press
2012
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3499055/ https://ncbi.nlm.nih.gov/pubmed/22505655 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgs145 |
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