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Structural Basis for p300 Taz2/p53 TAD1 Binding and Modulation by Phosphorylation
Coactivators CBP and p300 play important roles in mediating the transcriptional activity of p53. Until now, however, no detailed structural information has been available on how any of the domains of p300 interact with p53. Here, we report the NMR structure of the complex of the Taz2 (C/H3) domain o...
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| 主要な著者: | , , , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2009
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2705179/ https://ncbi.nlm.nih.gov/pubmed/19217391 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2008.12.009 |
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