Protection from α-Synuclein induced dopaminergic neurodegeneration by overexpression of the mitochondrial import receptor TOM20

Dopaminergic neurons of the substantia nigra are selectively vulnerable to mitochondrial dysfunction, which is hypothesized to be an early and fundamental pathogenic mechanism in Parkinson’s disease (PD). Mitochondrial function depends on the successful import of nuclear-encoded proteins, many of wh...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:NPJ Parkinsons Dis
Egile Nagusiak: De Miranda, Briana R., Rocha, Emily M., Castro, Sandra L., Greenamyre, J. Timothy
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group UK 2020
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7722884/
https://ncbi.nlm.nih.gov/pubmed/33293540
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41531-020-00139-6
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