The industrial solvent trichloroethylene induces LRRK2 kinase activity and dopaminergic neurodegeneration in a rat model of Parkinson’s disease

Gene-environment interaction is implicated in the majority of idiopathic Parkinson’s disease (PD) risk, and some of the most widespread environmental contaminants are selectively toxic to dopaminergic neurons. Pesticides have long been connected to PD incidence, however, it has become increasingly a...

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Bibliografische gegevens
Gepubliceerd in:Neurobiol Dis
Hoofdauteurs: De Miranda, Briana R., Castro, Sandra L., Rocha, Emily M., Bodle, Christopher R., Johnson, Katrina E., Greenamyre, J. Timothy
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2021
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8026730/
https://ncbi.nlm.nih.gov/pubmed/33636387
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2021.105312
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