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Distal and proximal hypoxia response elements co-operate to regulate organ-specific erythropoietin gene expression
While it has been well-established that distal hypoxia response elements (HRE) regulate hypoxia-inducible factor (HIF) target genes such as erythropoietin (Epo), an interplay between multiple distal and proximal (promoter) HRE has not yet been described. Hepatic Epo expression is regulated by an HRE...
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| 出版年: | Haematologica |
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| 主要な著者: | , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Fondazione Ferrata Storti
2019
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7716368/ https://ncbi.nlm.nih.gov/pubmed/33256376 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2019.236406 |
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