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Estrogen-dependent downregulation of hypoxia-inducible factor (HIF)-2α in invasive breast cancer cells
The involvement of estrogen (E2) and hypoxia in tumor progression is well established. Hypoxia has been reported to activate and degrade estrogen receptor alpha (ERα) in breast cancer cells. Furthermore, E2 has been shown to regulate hypoxia-inducible factor (HIF)-1α protein, but its role in HIF-2α...
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| Pubblicato in: | Oncotarget |
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| Autori principali: | , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Impact Journals LLC
2016
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5058746/ https://ncbi.nlm.nih.gov/pubmed/27105516 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.8866 |
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