Differential prognostic impact of hypoxia induced and diffuse HIF-1α expression in invasive breast cancer

Background: Intratumorous hypoxia triggers a broad cellular response mediated by the transcription factor hypoxia inducible factor 1 (HIF-1). HIF-1α concentrations increase during breast carcinogenesis, and are associated with poor prognosis. An earlier study noted two HIF-1α overexpression patterns...

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Autori principali: Vleugel, M M, Greijer, A E, Shvarts, A, van der Groep, P, van Berkel, M, Aarbodem, Y, van Tinteren, H, Harris, A L, van Diest, P J, van der Wall, E
Natura: Artigo
Lingua:Inglês
Pubblicazione: Copyright 2005 Journal of Clinical Pathology 2005
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Original Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1770566/
https://ncbi.nlm.nih.gov/pubmed/15677538
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jcp.2004.019885
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