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Expression of hypoxia-inducible factor-1α and cell cycle proteins in invasive breast cancer are estrogen receptor related

BACKGROUND: The transcription factor hypoxia-inducible factor-1 (HIF-1) is a key regulator of the cellular response to hypoxia. Previous studies showed that concentrations of its subunit HIF-1α, as a surrogate for HIF-1 activity, are increased during breast carcinogenesis and can independently predi...

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Autors principals: Bos, Reinhard, van Diest, Paul J, van der Groep, Petra, Shvarts, Avi, Greijer, Astrid E, van der Wall, Elsken
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2004
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC468666/
https://ncbi.nlm.nih.gov/pubmed/15217513
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/bcr813
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