No Amplifications of Hypoxia-Inducible Factor-1α Gene in Invasive Breast Cancer: A Tissue Microarray Study

Objective: Hypoxia Inducible Factor‐1 (HIF‐1) is an important transcription factor that stimulates tumour growth and metastases via several pathways, including angiogenesis and altered metabolism. Activation of HIF‐1 depends on the levels of its α‐subunit, which increase during hypoxia. Recent studi...

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Udgivet i:Cell Oncol
Main Authors: Vleugel, Marije M., Bos, Reinhard, Buerger, Horst, van der Groep, Petra, Saramäki, Outi R., Visakorpi, Tapio, van der Wall, Elsken, van Diest, Paul J.
Format: Artigo
Sprog:Inglês
Udgivet: IOS Press 2004
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Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4612258/
https://ncbi.nlm.nih.gov/pubmed/15623945
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2004/532413
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