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Subcellular FIH-1 expression patterns in invasive breast cancer in relation to HIF-1α expression

BACKGROUND: Hypoxia Inducible Factor-1α (HIF-1α) expression in breast cancer is associated with a poor clinical outcome. HIF-1α shows two expression patterns: the canonical poor prognosis hypoxia-related perinecrotic pattern and a diffuse expression pattern that seems to have less downstream effects...

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Bibliographic Details
Main Authors: Hyseni, Agon, van der Groep, Petra, van der Wall, Elsken, van Diest, Paul J.
Format: Artigo
Language:Inglês
Published: Springer Netherlands 2011
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3223342/
https://ncbi.nlm.nih.gov/pubmed/21732131
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13402-011-0053-5
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