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Necrosis related HIF-1α expression predicts prognosis in patients with endometrioid endometrial carcinoma
BACKGROUND: Hypoxia inducible factor 1α (HIF-1α) plays an essential role in the adaptive response of cells to hypoxia and is associated with aggressive tumour behaviour. We have shown p27(kip1), which is generally reduced in endometrial cancer, to be re-expressed in hypoxic regions. This possibly co...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
BioMed Central
2010
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2909981/ https://ncbi.nlm.nih.gov/pubmed/20565904 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-10-307 |
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