IMMU-11. LOCOREGIONAL DELIVERY OF TRANSIENT GD2 CAR T CELLS FOR SAFE AND EFFECTIVE TREATMENT OF DIPG

Diffuse intrinsic pontine glioma (DIPG) is a universally fatal pediatric brain tumor with a median survival of one year. Recently Mount et al (Nat Med 2018) discovered the disialoganglioside GD2 is present at high levels on the surface of DIPG and can be targeted using GD2-directed CAR T cells. Howe...

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發表在:Neuro Oncol
Main Authors: Foster, Jessica, Griffin, Crystal, Stern, Allison, Brimley, Cameron, Smith, Tiffany, Storm, Phillip, Resnick, Adam
格式: Artigo
語言:Inglês
出版: Oxford University Press 2020
主題:
Immunotherapy
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7715362/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noaa222.367
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