IMMU-17. USE OF MRNA FOR SAFE AND EFFECTIVE GD2-DIRECTED CAR T CELLS TO TREAT DIFFUSE MIDLINE GLIOMAS

Chimeric antigen receptor (CAR) T cells targeting the disialoganglioside GD2 have garnered interest as an effective therapeutic for treating diffuse midline glioma (DMG). However, prior studies raised significant concerns of neurotoxicity and fatality when using virally transduced CAR T cells agains...

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Bibliografiska uppgifter
I publikationen:Neuro Oncol
Huvudupphovsmän: Foster, Jessica, Griffin, Crystal, Stern, Allison, Brimley, Cameron, Storm, Phillip, Barrett, David, Resnick, Adam
Materialtyp: Artigo
Språk:Inglês
Publicerad: Oxford University Press 2021
Ämnen:
Immunology/Immunotherapy
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC8168104/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noab090.124
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