IMMU-04. DEVELOPMENT OF GPC2-DIRECTED CHIMERIC ANTIGEN RECEPTOR THERAPY FOR PEDIATRIC BRAIN TUMORS WITH IN VITRO TRANSCRIBED mRNA

The recent identification of glypican-2 (GPC2) as a cell surface oncoprotein in neuroblastoma, high grade glioma (HGG), and medulloblastoma provides the opportunity for the development of targeted immunotherapy. We hypothesized that chimeric antigen receptor (CAR) T cell therapy directed against GPC...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Neuro Oncol
Prif Awduron: Foster, Jessica B, Griffin, Crystal, Stern, Allison, Brimley, Cameron, Lane, Maria, Buongervino, Samantha, Dimitrov, Dimiter S, Barrett, David M, Resnick, Adam C, Maris, John M, Bosse, Kristopher R
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Oxford University Press 2019
Pynciau:
Immunology/Immunotherapy
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6477251/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz036.125
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!

Eitemau Tebyg