IMMU-16. TARGETING GLYPICAN 2 (GPC2) ON PEDIATRIC MALIGNANT BRAIN TUMORS WITH MRNA CAR T CELLS

Glypican 2 (GPC2) is a cell-surface oncoprotein initially identified in neuroblastoma, retinoblastoma, and medulloblastoma as an ideal target for immunotherapy (Cancer Cell, 2017). Here we evaluated GPC2 expression across the spectrum of pediatric brain tumors using RNA sequencing from specimens in...

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Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Foster, Jessica, Griffin, Crystal, Stern, Allison, Brimley, Cameron, Buongervino, Samantha, Storm, Phillip, Barrett, David, Maris, John, Resnick, Adam, Bosse, Kristopher
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2021
Assuntos:
Immunology/Immunotherapy
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8168182/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noab090.123
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