IMMU-16. TARGETING GLYPICAN 2 (GPC2) ON PEDIATRIC MALIGNANT BRAIN TUMORS WITH MRNA CAR T CELLS

Glypican 2 (GPC2) is a cell-surface oncoprotein initially identified in neuroblastoma, retinoblastoma, and medulloblastoma as an ideal target for immunotherapy (Cancer Cell, 2017). Here we evaluated GPC2 expression across the spectrum of pediatric brain tumors using RNA sequencing from specimens in...

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Détails bibliographiques
Publié dans:Neuro Oncol
Auteurs principaux: Foster, Jessica, Griffin, Crystal, Stern, Allison, Brimley, Cameron, Buongervino, Samantha, Storm, Phillip, Barrett, David, Maris, John, Resnick, Adam, Bosse, Kristopher
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2021
Sujets:
Immunology/Immunotherapy
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8168182/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noab090.123
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