IMMU-11. LOCOREGIONAL DELIVERY OF TRANSIENT GD2 CAR T CELLS FOR SAFE AND EFFECTIVE TREATMENT OF DIPG

Diffuse intrinsic pontine glioma (DIPG) is a universally fatal pediatric brain tumor with a median survival of one year. Recently Mount et al (Nat Med 2018) discovered the disialoganglioside GD2 is present at high levels on the surface of DIPG and can be targeted using GD2-directed CAR T cells. Howe...

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Foilsithe in:Neuro Oncol
Main Authors: Foster, Jessica, Griffin, Crystal, Stern, Allison, Brimley, Cameron, Smith, Tiffany, Storm, Phillip, Resnick, Adam
Formáid: Artigo
Teanga:Inglês
Foilsithe: Oxford University Press 2020
Ábhair:
Immunotherapy
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7715362/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noaa222.367
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