MBRS-24. FUNCTIONAL CHARACTERIZATION OF IKBKAP/ELP1 AS A NOVEL SHH MEDULLOBLASTOMA PREDISPOSITION GENE

Medulloblastoma (MB), a common malignant pediatric brain tumor, comprises at least four distinct molecular entities: WNT, SHH, Group 3, and Group 4. SHH-MB is driven by aberrant activation of the Sonic hedgehog (SHH) pathway in granule neuron progenitors (GNPs) and is associated with hereditary canc...

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Bibliographische Detailangaben
Veröffentlicht in:Neuro Oncol
Hauptverfasser: Lopez, Jesus Garcia, Kutscher, Lena, Kojic, Marija, Gudenas, Brian, Smith, Kyle, Hadley, Jennifer, Gajjar, Amar, Robinson, Giles W, Pfister, Stefan M, Wainwright, Brandon J, Kawauchi, Daisuke, Northcott, Paul A
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2020
Schlagworte:
Medulloblastoma (Research)
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7715295/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noaa222.540
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