MBRS-07. BCOR LOSS IMPACTS SHH MEDULLOBLASTOMA FORMATION VIA TRANSCRIPTIONAL UP-REGULATION OF Igf2

Sonic hedgehog (SHH) medulloblastoma (MB(SHH)) accounts for approximately 25% of all MB diagnoses and is the predominant disease subgroup in infants and adults. In addition to obligatory constitutive activation of SHH signaling, previous studies have indicated the requirement of secondary genetic hi...

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Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Kawauchi, Daisuke, Clark, Jessica, Okonechnikov, Konstantin, Batora, Nadja, Vouri, Mikaella, van Rijn, Sjoerd, Gearhart, Micah, Orr, Brent, Korshunov, Andrey, Kool, Marcel, Bardwell, Vivian, Pfister, Stefan, Northcott, Paul
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6012775/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy059.453
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