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Synthesis and antiviral evaluation of fluorinated acyclo-nucleosides and their phosphoramidates
A novel series of tetrafluoro and hexafluoro acyclic nucleosides and their phosphoramidates were successfully prepared from commercially available 2,2,3,3-tetrafluoro-1,4-butanediol and 2,2,3,3,4,4-hexafluoro-1,5-pentanediol in four to six steps. Their ability to block HIV, HCV, HSV-1, and HBV repli...
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| Publicado no: | Nucleosides Nucleotides Nucleic Acids |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7714494/ https://ncbi.nlm.nih.gov/pubmed/27759481 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15257770.2016.1218023 |
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