A role for LSH in facilitating DNA methylation by DNMT1 through enhancing UHRF1 chromatin association

LSH, a SNF2 family DNA helicase, is a key regulator of DNA methylation in mammals. How LSH facilitates DNA methylation is not well defined. While previous studies with mouse embryonic stem cells (mESc) and fibroblasts (MEFs) derived from Lsh knockout mice have revealed a role of Lsh in de novo DNA m...

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Dettagli Bibliografici
Pubblicato in:Nucleic Acids Res
Autori principali: Han, Mengmeng, Li, Jialun, Cao, Yaqiang, Huang, Yuanyong, Li, Wen, Zhu, Haijun, Zhao, Qian, Han, Jing-Dong Jackie, Wu, Qihan, Li, Jiwen, Feng, Jing, Wong, Jiemin
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2020
Soggetti:
Gene regulation, Chromatin and Epigenetics
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7708066/
https://ncbi.nlm.nih.gov/pubmed/33170271
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkaa1003
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