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A role for LSH in facilitating DNA methylation by DNMT1 through enhancing UHRF1 chromatin association
LSH, a SNF2 family DNA helicase, is a key regulator of DNA methylation in mammals. How LSH facilitates DNA methylation is not well defined. While previous studies with mouse embryonic stem cells (mESc) and fibroblasts (MEFs) derived from Lsh knockout mice have revealed a role of Lsh in de novo DNA m...
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| Publicado no: | Nucleic Acids Res |
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| Main Authors: | , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7708066/ https://ncbi.nlm.nih.gov/pubmed/33170271 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkaa1003 |
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