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Structural distinctions between NAD(+) riboswitch domains 1 and 2 determine differential folding and ligand binding
Riboswitches are important gene regulatory elements frequently encountered in bacterial mRNAs. The recently discovered nadA riboswitch contains two similar, tandemly arrayed aptamer domains, with the first domain possessing high affinity for nicotinamide adenine dinucleotide (NAD(+)). The second dom...
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| Publicat a: | Nucleic Acids Res |
|---|---|
| Autors principals: | , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Oxford University Press
2020
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7708056/ https://ncbi.nlm.nih.gov/pubmed/33170270 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkaa1029 |
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