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Structural distinctions between NAD(+) riboswitch domains 1 and 2 determine differential folding and ligand binding
Riboswitches are important gene regulatory elements frequently encountered in bacterial mRNAs. The recently discovered nadA riboswitch contains two similar, tandemly arrayed aptamer domains, with the first domain possessing high affinity for nicotinamide adenine dinucleotide (NAD(+)). The second dom...
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| 發表在: | Nucleic Acids Res |
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| Main Authors: | , , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Oxford University Press
2020
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7708056/ https://ncbi.nlm.nih.gov/pubmed/33170270 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkaa1029 |
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