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Structure and ligand binding of the ADP-binding domain of the NAD(+) riboswitch

The nadA motif is the first known NAD(+)-dependent riboswitch, comprising two similar tandem bulged stem–loop structures. We have determined the structure of the 5′ domain 1 of the riboswitch. It has three coaxial helical segments, separated by an ACANCCCC bulge and by an internal loop, with a terti...

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Bibliographic Details
Published in:RNA
Main Authors: Huang, Lin, Wang, Jia, Lilley, David M.J.
Format: Artigo
Language:Inglês
Published: Cold Spring Harbor Laboratory Press 2020
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7297122/
https://ncbi.nlm.nih.gov/pubmed/32295864
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.074898.120
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